Description
InformationJaceosidin, a flavonoid isolated from Artemisia vestita, possesses anti-tumor and anti-proliferative activities in many cancer cells. Jaceosidin inducesapoptosis, activatesBaxand down-regulatesMcl-1andc-FLIPexpression. Jaceosidin inhibitsCOX-2expression andNF-κBactivation.TargetsBax ; Mcl-1 ; c-FLIP ; COX-2 ; NF-κB